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Although mutations in rpsA and panD have been reported in PZA resistance, their contributions are considered less significant compared to pncA and require further validation (Liu et al., 2018)

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Using laser capture microdissection followed by label‐free shotgun proteomics analysis, we show that the glomerular proteome in old mice was characterized by decreased abundance of cytoskeletal proteins (critical for maintaining normal glomerular function) and heat shock proteins, leading to increased accumulation of apolipoprotein E and inflammatory molecules